Abstract The 2.75x100 abnormal structure of tumor vascular seriously hinders the delivery and deep penetration of drug in tumor therapy.Herein, an integrated and tumor microenvironment (TME)-responsive nanocarrier is designed, which can dilate vessle and improve the drug penetration by in situ releasing nitric oxide (NO).Briefly, S-nitroso-glutathi
The adult human cochlea contains various types of peripheral glial cells that envelop or myelinate the three different domains of the spiral ganglion neurons: the central processes in the cochlear nerve, the cell bodies in the spiral ganglia, and the peripheral processes in the osseous spiral lamina.Little is known about the distribution, lineage s
Nowadays, there is an extensive production and use of plastic materials for different industrial activities.These plastics, either from their primary production sources or through their own degradation processes, can contaminate ecosystems with micro- and nanoplastics.Once in the aquatic environment, these microplastics can be the basis for the ads
The stratospheric ozone layer plays a crucial role in protecting living organisms against ultraviolet radiation.Chlorofluorocarbons (CFC) contained in metered-dose inhalers (MDIs) contribute fig leaf apron to ozone depletion and in accordance with the Montreal Protocol on Substances That Deplete the Ozone Layer established 10 years ago, phase-out s
The Greater Yellowstone Ecosystem (GYE), located in the Central Rocky Mountains of western North America, is one of the largest nearly intact temperate-zone ecosystems on Earth.Here, Lactarius is an important component of ectomycorrhizal communities in many habitat types, from low elevation riparian areas to high elevation conifer forests and alpin